Incidence, prevalence and risk factors of delirium in ICU patients: A systematic review and meta‐analysis

作者：Nan‐Nan Wu, Ya‐Bin Zhang, Shu‐Yun Wang, Yuhua Zhao, Xuemei Zhong · 发表于：Nursing in Critical Care · 年份：2022 · DOI：10.1111/nicc.12857 · 被引用次数：44 · 研究领域：Intensive Care Unit Cognitive Disorders、Family and Patient Care in Intensive Care Units、Anesthesia and Sedative Agents

Abstract Background Delirium is one of the most common problems in intensive care units (ICU), and it has a detrimental influence on the patients' health. Estimating the prevalence of delirium in ICU patients and understanding the risk factors for delirium are crucial tasks. Aim To offer empirical support for early detection of the risk of delirium in ICU patients, we conducted a systematic review and meta‐analysis to analyse the incidence, prevalence and risk factors of delirium in ICU patients. Study Design From inception to 19th December 2021, PubMed, Embase, Cochrane Library, Web of Science, China Knowledge Resource Integrated Database (CNKI), Wanfang Database, Chinese Biomedical Database (CBM) and Weipu Database (VIP) were searched for inclusion to the study. The quality of the included studies was assessed by two investigators independently. The outcomes of the meta‐analysis, which was conducted using the Stata 12.0 software, were reported using odds ratios (OR) and 95 percent confidence intervals (CI). Heterogeneity was determined using the I 2 statistic. Results In this meta‐analysis, 51 studies with a total of 39 076 patients were evaluated. The incidence and prevalence of delirium in ICU patients were 31 per 1000 and 33%, respectively. A total of 28 risk factors were identified. Of these 28 risk factors, the top five modifiable risk factors were pain (OR = 19.74, 95% CI [8.86–30.61]), use of physical restraints (OR = 15.46, 95% CI [3.68–27.25]), respiratory diseases...