The Antibacterial Activity of Kaempferol Combined with Colistin against Colistin-Resistant Gram-Negative Bacteria

作者：Huijing Zhou, Mengxin Xu, Wenhui Guo, Zhuocheng Yao, Xin Du, Lijiang Chen, Yao Sun, Yishi Shi, Jianming Cao, Tieli Zhou · 发表于：Microbiology Spectrum · 年份：2022 · DOI：10.1128/spectrum.02265-22 · 被引用次数：47 · 研究领域：Antibiotic Resistance in Bacteria、Phenothiazines and Benzothiazines Synthesis and Activities、Pharmacological Effects of Natural Compounds

. The synergistic effect of combined application may be attributed to membrane permeability. Due to the low cytotoxicity of the combined concentration, the combination exhibits a promising future for use in clinical anti-infection treatments. This finding might broaden the potential applications for COL.