Bifidobacterium animalis Promotes the Growth of Weaning Piglets by Improving Intestinal Development, Enhancing Antioxidant Capacity, and Modulating Gut Microbiota

作者：Jiaman Pang, Yisi Liu, Luyuan Kang, Hao Ye, Jianjun Zang, Junjun Wang, Dandan Han · 发表于：Applied and Environmental Microbiology · 年份：2022 · DOI：10.1128/aem.01296-22 · 被引用次数：48 · 研究领域：Gut microbiota and health、Probiotics and Fermented Foods、Animal Nutrition and Physiology

In the modern swine industry, weaning is a critical period in the pig's life cycle. Sudden dietary, social, and environmental changes can easily lead to gut microbiota dysbiosis, diarrhea, and a decrease in growth performance. To stabilize intestinal microbiota and promote animal growth, antibiotics were widely applied in swine diets during the past few decades. However, the side effects of antibiotics posed a great threat to public health and food safety. Therefore, it is urgent to find and develop antibiotic alternatives. The growing evidence suggested that probiotics can be preferable alternatives to antibiotics because they can modulate microbiota composition and resist pathogens colonization. In this study, our results indicated that dietary supplementation with Bifidobacterium animalis promoted growth in weaning piglets by improving gut development, increasing beneficial bacteria abundances, and declining pathogens populations.