Similarities and differences between SUNCT and SUNA: a cross-sectional, multicentre study of 76 patients in China

作者：Shuhua Zhang, Ya Cao, Fanhong Yan, Sufen Chen, Wei Gui, Dongmei Hu, Huanxian Liu, Hongjin Li, Rongce Yu, Wei Dan, Xiaolin Wang, Rongfei Wang, Xiaoyan Chen, Mingjie Zhang, Ye Ran, Zhihua Jia, Xun Han, Mianwang He, Jing Liu, Shengyuan Yu, Zhao Dong · 发表于：The Journal of Headache and Pain · 年份：2022 · DOI：10.1186/s10194-022-01509-6 · 被引用次数：14 · 研究领域：Migraine and Headache Studies、Trigeminal Neuralgia and Treatments、Myofascial pain diagnosis and treatment

BACKGROUND: Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) have not been evaluated sufficiently due to limited data, particularly in China. METHODS: Patients with SUNCT or SUNA treated in a tertiary headache centre or seven other headache clinics of China between April 2009 and July 2022 were studied; we compared their demographics and clinical phenotypes. RESULTS: The 45 patients with SUNCT and 31 patients with SUNA had mean ages at onset of 37.22 ± 14.54 years and 42.45 ± 14.72 years, respectively. The mean ages at diagnosis of SUNCT and SUNA were 41.62 ± 12.70 years and 48.68 ± 13.80 years, respectively (p = 0.024). The correct diagnosis of SUNCT or SUNA was made after an average of 2.5 (0-20.5) years or 3.0 (0-20.7) years, respectively. Both diseases had a female predominance (SUNCT: 1.14:1; SUNA: 2.10:1). The two diseases differed in the most common attack site (temporal area in SUNCT, p = 0.017; parietal area in SUNA, p = 0.002). Qualitative descriptions of the attacks included stabbing pain (44.7%), electric-shock-like pain (36.8%), shooting pain (25.0%), and slashing pain (18.4%). Lacrimation was the most common autonomic symptom in both SUNCT and SUNA patients, while eyelid oedema, ptosis, and miosis were less frequent. Triggers such as cold air and face washing were shared by the two diseases, and they were consist...