The Impact of the COVID-19 Pandemic and Associated Control Measures on the Mental Health of the General Population

作者：Georgia Salanti, Natalie Peter, Thomy Tonia, Alexander Holloway, Ian R. White, Leila Darwish, Nicola Low, Matthias Egger, Andreas D. Haas, Seena Fazel, Ronald C. Kessler, Helen Herrman, Christian Kieling, Dominique J.‐F. de Quervain, Simone N. Vigod, Vikram Patel, Tianjing Li, Pim Cuijpers, Andrea Cipriani, Toshi A. Furukawa, Stefan Leucht, MHCOVID Crowd Investigators, Abdulkadir Usman Sambo, Akira Onishi, Akira Sato, Alessandro Rodolico, Ana Cristina de Oliveira Solis, Anastasia Antoniou, Angelika Kapfhammer, Anna Ceraso, Aoife O’Mahony, Aurélie M. Lasserre, Aziz Mert Ipekci, Carmen Concerto, Caroline Zangani, Chinonso Nwamaka Igwesi-Chidobe, Christina Diehm, Dicle Dilay Demir, Dongfang Wang, Edoardo G. Ostinelli, Ethan Sahker, Gabriel Henrique Beraldi, Gamze Erzın, Harrison Nelson, Hélio Elkis, Hissei Imai, Hui Wu, Ilias Kamitsis, Ioannis Filis, Ioannis Michopoulos, Irene Bighelli, James S. W. Hong, Javier Ballesteros, Katharine Smith, Kazufumi Yoshida, Kenji Omae, Marialena Trivella, Masafumi Tada, Matthias A. Reinhard, Michael J. Ostacher, Monika Müller, Nathalia Gonzalez Jaramillo, Panagiotis Ferentinos, Rie Toyomoto, Samuele Cortese, Sanae Kishimoto, Sergio A. Covarrubias-Castillo, Spyridon Siafis, Trevor Thompson, Vasilios Karageorgiou, Virginia Chiocchia, Yikang Zhu, Yukiko Honda, Abdulkadir Usman Sambo, Akira Onishi, Akira Sato, Alessandro Rodolico, Ana Cristina de Oliveira Solis, Anastasia Antoniou, Angelika Kapfhammer, Anna Ceraso, Aoife O’Mahony, Aurélie M. Lasserre, Aziz Mert Ipekci, Carmen Concerto, Caroline Zangani, Chinonso Nwamaka Igwesi-Chidobe, Christina Diehm, Dicle Dilay Demir, Dongfang Wang, Edoardo G. Ostinelli, Ethan Sahker, Gabriel Henrique Beraldi, Gamze Erzın, Harrison Nelson, Hélio Elkis, Hissei Imai, Hui Wu, Ilias Kamitsis, Ioannis Filis, Ioannis Michopoulos, Irene Bighelli, James S. W. Hong, Javier Ballesteros, Katharine Smith, Kazufumi Yoshida, Kenji Omae, Marialena Trivella, Masafumi Tada, Matthias A. Reinhard, Michael J. Ostacher, Monika Müller, Nathalia Gonzalez Jaramillo, Panagiotis Ferentinos, Rie Toyomoto, Samuele Cortese, Sanae Kishimoto, Sergio A. Covarrubias-Castillo, Spyridon Siafis, Trevor Thompson, Vasilios Karageorgiou, Virginia Chiocchia, Yikang Zhu, Yukiko Honda · 发表于：Annals of Internal Medicine · 年份：2022 · DOI：10.7326/m22-1507 · 被引用次数：192 · 研究领域：COVID-19 and Mental Health、Long-Term Effects of COVID-19、Mental Health Treatment and Access

BACKGROUND: To what extent the COVID-19 pandemic and its containment measures influenced mental health in the general population is still unclear. PURPOSE: To assess the trajectory of mental health symptoms during the first year of the pandemic and examine dose-response relations with characteristics of the pandemic and its containment. DATA SOURCES: Relevant articles were identified from the living evidence database of the COVID-19 Open Access Project, which indexes COVID-19-related publications from MEDLINE via PubMed, Embase via Ovid, and PsycInfo. Preprint publications were not considered. STUDY SELECTION: Longitudinal studies that reported data on the general population's mental health using validated scales and that were published before 31 March 2021 were eligible. DATA EXTRACTION: An international crowd of 109 trained reviewers screened references and extracted study characteristics, participant characteristics, and symptom scores at each timepoint. Data were also included for the following country-specific variables: days since the first case of SARS-CoV-2 infection, the stringency of governmental containment measures, and the cumulative numbers of cases and deaths. DATA SYNTHESIS: In a total of 43 studies (331 628 participants), changes in symptoms of psychological distress, sleep disturbances, and mental well-being varied substantially across studies. On average, depression and anxiety symptoms worsened in the first 2 months of the pandemic (standardized mean diffe...