Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors

作者：Dou Dou, Jie Wang, Yunjin Qiao, Gulinuer Wumaier, Wenjie Sha, Wenjie Li, Wenyi Mei, Tingyuan Yang, Chen Zhang, Huan He, Caolin Wang, Linna Chu, Baihui Sun, Rongrong Su, Xiangyu Ma, Mengdie Gong, Xie Lijuan, Wenzhe Jiang, Yanyan Diao, Lili Zhu, Zhenjiang Zhao, Zhuo Chen, Yufang Xu, Shengqing Li, Honglin Li · 发表于：European Journal of Medicinal Chemistry · 年份：2022 · DOI：10.1016/j.ejmech.2022.114856 · 被引用次数：27 · 研究领域：Lung Cancer Treatments and Mutations、Cancer therapeutics and mechanisms、Lung Cancer Research Studies