Concerted expansion and contraction of immune receptor gene repertoires in plant genomes

作者：Bruno Pok Man Ngou, Robert Heal, Michele Wyler, Marc W. Schmid, Jonathan D. G. Jones · 发表于：Nature Plants · 年份：2022 · DOI：10.1038/s41477-022-01260-5 · 被引用次数：134 · 研究领域：Plant-Microbe Interactions and Immunity、Plant Pathogenic Bacteria Studies、Plant Parasitism and Resistance

Recent reports suggest that cell-surface and intracellular immune receptors function synergistically to activate robust defence against pathogens, but whether they co-evolve is unclear. Here we determined the numbers of cell-surface and intracellular immune receptors in 350 species. Surprisingly, the number of receptor genes that are predicted to encode cell-surface and intracellular immune receptors is strongly correlated. We suggest this is consistent with mutual potentiation of immunity initiated by cell-surface and intracellular receptors being reflected in the concerted co-evolution of the size of their repertoires across plant species.