Blood cell formation in crustaceans

作者：Irene Söderhäll, Kenneth Söderhäll · 发表于：Fish & Shellfish Immunology · 年份：2022 · DOI：10.1016/j.fsi.2022.10.008 · 被引用次数：37 · 研究领域：Invertebrate Immune Response Mechanisms、Neurobiology and Insect Physiology Research、Insect Resistance and Genetics

In crustacean animals the hemocytes are key players in immunity and of crucial importance for the health of the animals. Hemocytes are mainly produced in the hematopoietic tissue and from there released into the circulation where they finally mature. In this review we summarize the latest findings about crustacean hemocyte formation. The role of the extracellular matrix and crosslinking enzyme transglutaminase is discussed. Moreover, important growth factors, transcriptional regulation and recent findings about inducers of hematopoiesis are covered. Finally, we discuss the use of different markers for classification of crustacean hemocytes.