neuromaps: structural and functional interpretation of brain maps

作者：Ross D. Markello, Justine Y. Hansen, Zhen-Qi Liu, Vincent Bazinet, Golia Shafiei, Laura E. Suárez, Nadia Blostein, Jakob Seidlitz, Sylvain Baillet, Theodore D. Satterthwaite, M. Mallar Chakravarty, Armin Raznahan, Bratislav Mišić · 发表于：Nature Methods · 年份：2022 · DOI：10.1038/s41592-022-01625-w · 被引用次数：506 · 研究领域：Functional Brain Connectivity Studies、Metabolomics and Mass Spectrometry Studies、Neural dynamics and brain function

Imaging technologies are increasingly used to generate high-resolution reference maps of brain structure and function. Comparing experimentally generated maps to these reference maps facilitates cross-disciplinary scientific discovery. Although recent data sharing initiatives increase the accessibility of brain maps, data are often shared in disparate coordinate systems, precluding systematic and accurate comparisons. Here we introduce neuromaps, a toolbox for accessing, transforming and analyzing structural and functional brain annotations. We implement functionalities for generating high-quality transformations between four standard coordinate systems. The toolbox includes curated reference maps and biological ontologies of the human brain, such as molecular, microstructural, electrophysiological, developmental and functional ontologies. Robust quantitative assessment of map-to-map similarity is enabled via a suite of spatial autocorrelation-preserving null models. neuromaps combines open-access data with transparent functionality for standardizing and comparing brain maps, providing a systematic workflow for comprehensive structural and functional annotation enrichment analysis of the human brain.