The Relationship Between Sleep Traits and Tinnitus in UK Biobank: A Population-Based Cohort Study

作者：Jiajia Peng, Yijun Dong, Yaxin Luo, Ke Qiu, Danni Cheng, Yufang Rao, Yao Song, Wendu Pang, Xiaosong Mu, Chunhong Hu, Hongchang Chen, Wei Zhang, Wei Xu, Jianjun Ren, Yu Zhao · 发表于：Ear and Hearing · 年份：2022 · DOI：10.1097/aud.0000000000001273 · 被引用次数：14 · 研究领域：Hearing, Cochlea, Tinnitus, Genetics、Cerebral Venous Sinus Thrombosis、Multisensory perception and integration

OBJECTIVES: Understanding the association between sleep traits and tinnitus could help prevent and provide appropriate interventions against tinnitus. Therefore, this study aimed to assess the relationship between different sleep patterns and tinnitus. DESIGN: A cross-sectional analysis using baseline data (2006-2010, n = 168,064) by logistic regressions was conducted to evaluate the association between sleep traits (including the overall health sleep score and five sleep behaviors) and the occurrence (yes/no), frequency (constant/transient), and severity (upsetting/not upsetting) of tinnitus. Further, a prospective analysis of participants without tinnitus at baseline (n = 9581) was performed, who had been followed-up for 7 years (2012-2019), to assess the association between new-onset tinnitus and sleep characteristics. Moreover, a subgroup analysis was also carried out to estimate the differences in sex by dividing the participants into male and female groups. A sensitivity analysis was also conducted by excluding ear-related diseases to avoid their confounding effects on tinnitus (n = 102,159). RESULTS: In the cross-sectional analysis, participants with "current tinnitus" (OR: 1.13, 95% CI: 1.04-1.22, p = 0.004) had a higher risk of having a poor overall healthy sleep score and unhealthy sleep behaviors such as short sleep durations (OR: 1.09, 95% CI: 1.04-1.14, p < 0.001), late chronotypes (OR: 1.09, 95% CI: 1.05-1.13, p < 0.001), and sleeplessness (OR: 1.16, 95% CI: 1.1...