Author response: Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME

作者：Zikai Zhao, Qi Li, Usama Ashraf, Mengjie Yang, Wenjing Zhu, Jun Gu, Zheng Chen, Changqin Gu, Youhui Si, Shengbo Cao, Jing Ye · 年份：2022 · DOI：10.7554/elife.73792.sa2 · 被引用次数：1 · 研究领域：COVID-19 Impact on Reproduction、Mosquito-borne diseases and control、Autoimmune and Inflammatory Disorders Research

Zika virus infection induces the gasdermin E-mediated pyroptosis in placental cells through TNF-α-caspase-8-caspase-3 signaling pathway, which contributes to adverse fetal outcomes in pregnant mouse model.