Bidentate Ru(II)-NC Complex as a Catalyst for Semihydrogenation of Azoarenes to Hydrazoarenes with Ethanol

作者：Dawei Gong, Degong Kong, Na Xu, Yuhui Hua, Bo Liu, Zhanlin Xu · 发表于：Organic Letters · 年份：2022 · DOI：10.1021/acs.orglett.2c02866 · 被引用次数：34 · 研究领域：Asymmetric Hydrogenation and Catalysis、Carbon dioxide utilization in catalysis、Nanomaterials for catalytic reactions

The transfer hydrogenation of azoarenes to hydrazoarenes using ethanol as a hydrogen source by a bidentate Ru(II)-NC complex is developed. A weak base is crucial for this semihydrogenation that can efficiently avoid hydrazoarene dehydrogenation under strongly basic conditions. Control experiments and density functional theory calculations demonstrate the mechanism via a Meerwein-Ponndorf-Verley mechanism, and the only byproduct is ethyl acetate. This study offers a new and simple approach for the synthesis of hydrazoarenes.