Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial

作者：Ashkan Shoamanesh, Hardi Mundl, Eric E. Smith, Jaime Masjuán, Ivan Milanov, Teruyuki Hirano, Alina Agafina, Bruce Campbell, Valeria Caso, Jean‐Louis Mas, Qiang Dong, Peter Turčáni, Hanne Christensen, José M. Ferro, Roland Veltkamp, Robert Mikulík, Gian Marco De Marchis, Thompson Robinson, Robin Lemmens, Adam Stępień, Stefan Greisenegger, Risto O. Roine, László Csiba, Pooja Khatri, Jonathan M. Coutinho, Arne Lindgren, Andrew M. Demchuk, Pablo Colorado, Bodo Kirsch, Christoph Neumann, Laura Heenan, Lizhen Xu, Stuart J. Connolly, Robert G. Hart · 发表于：The Lancet · 年份：2022 · DOI：10.1016/s0140-6736(22)01588-4 · 被引用次数：203 · 研究领域：Coagulation, Bradykinin, Polyphosphates, and Angioedema、Atrial Fibrillation Management and Outcomes、Thyroid and Parathyroid Surgery