pH/Thermosensitive dual-responsive hydrogel based sequential delivery for site-specific acute limb ischemia treatment

作者：Teng Zhang, Huan Ouyang, Shichen Liu, Xiong Lei, Zhiwei Zhong, Qingqing Wang, Zhuang Qiu, Yajia Ding, Weimin Zhou, Xiaolei Wang · 发表于：Journal of Materials Chemistry B · 年份：2022 · DOI：10.1039/d2tb00474g · 被引用次数：13 · 研究领域：Peripheral Artery Disease Management、Vascular Procedures and Complications、Polymer Surface Interaction Studies

A nanoplatform was developed to respond the changes of two different phases of acute limb ischemia, sequential releasing of drugs thus could be realized automatically to achieve in time cytoprotective and angiogenesis effects.