Progress in Traditional Chinese Medicine on Treatment of Diabetic Retinopathy

作者：Wencan Li, Wei Li, Qichang Xing, Zheng Liu, Yixiang Hu, Xiang Liu, Jiani Zhang · 发表于：Natural Product Communications · 年份：2022 · DOI：10.1177/1934578x221118547 · 被引用次数：7 · 研究领域：Retinal Diseases and Treatments、Neurological Disease Mechanisms and Treatments、Bioactive natural compounds

Diabetic retinopathy (DR), a common and blinding diabetic microvascular complication, is a harmful metabolic effect caused by persistent hyperglycemia. Owing to the complex pathogenesis of DR, various clinical treatment methods cannot completely prevent its development and are accompanied by various complications. Therefore, there is an urgent need to identify new therapeutic drugs or complementary and alternative therapies. Traditional Chinese medicine (TCM) has the unique advantages of multi-level, multi-target, and minimal side effects. Accumulating evidence has proven that TCM may help delay or prevent the progression of DR. This paper reviews the effect and mechanism of representative TCMs (including extracts, identified compounds, and compound formulas) on DR in recent years and provides evidence for new drug development and clinical efficacy.