Synergetic Dual-Site Atomic Catalysts for Sensitive Chemiluminescent Immunochromatographic Test Strips

作者：Jiaxin Xian, Shuai Luo, Jinxia Xue, Lvxia Zhang, Zhifeng Fu, Hui Ouyang · 发表于：Analytical Chemistry · 年份：2022 · DOI：10.1021/acs.analchem.2c02914 · 被引用次数：30 · 研究领域：Advanced Nanomaterials in Catalysis、Advanced biosensing and bioanalysis techniques、Nanocluster Synthesis and Applications

In view of the outstanding catalytic efficiency, single-atom catalysts (SACs) have shown great promise for the construction of sensitive chemiluminescent (CL) platforms. However, the low loading amount of active sites dramatically obstructs the improved catalytic activity of these metal SACs. Benefiting from the exceedingly unique catalytic properties of the metal–metal bonds, atomic clusters may give rise to enhancing the catalytic properties of SACs based on the synergistic effects of dual atomic-scale sites. Inspired by this, atomic Co 3 N clusters-assisted Co SACs (Co 3 N@Co SACs) were synthesized through a facile doping method. Through X-ray absorption spectroscopy, the active metal sites in the synergetic dual-site atomic catalysts of Co 3 N@Co SACs were confirmed to be Co–O 4 and Co 3 –N moieties. Co 3 N@Co SACs served as a superior co-reactant to remarkably enhance the luminol CL signal by 2155.0 times, which was prominently superior to the boosting effect of the pure Co SACs (98.4 times). The synergetic dual-site atomic catalysts contributed to accelerating the decomposition of H 2 O 2 into singlet oxygen as well as superoxide radical anions to display superb catalytic performances. For a concept employment, Co 3 N@Co SACs were attempted to utilize as CL probes for establishing a sensitive immunochromatographic assay to quantitate pesticide residues, in which imidacloprid was adopted as the model analyte. The quantitative range of imidacloprid was 0.05–10 ng mL –1 wi...