The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing

作者：Carlos Brites, Felice Deminco, Marcia Sampaio Sá, Jean Tadeu Brito, Estela Luz, Andreas Stöcker · 发表于：Viruses · 年份：2022 · DOI：10.3390/v14091841 · 被引用次数：14 · 研究领域：Poxvirus research and outbreaks、Bacillus and Francisella bacterial research、Herpesvirus Infections and Treatments

Monkeypox infection is rapidly spreading across the world. Despite the increasing number of cases, only a few reports have been published, and most are on people living without HIV. We report here the first two cases of monkeypox infection in Bahia, Brazil, one of them in a person living with HIV, on stable treatment. Both cases had a similar evolution, with a limited number of lesions and mild symptoms, with a complete recovery after 7-10 days. The potential route of transmission was via oral sex for the first case and was undefined for the second one. Both cases were confirmed through detection of the viral genome by PCR, and the partial sequence of the first case indicates the infection was caused by the West African clade. These cases confirm that monkeypox infection is currently being transmitted in Brazil and that people living with HIV on stable treatment are not likely to present a more severe form of monkeypox.