High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects

作者：Huawei Tong, Jia Huang, Qingquan Xiao, Bingbing He, Xue Dong, Yuanhua Liu, Xiali Yang, Dingyi Han, Zikang Wang, Xuchen Wang, Wenqin Ying, Runze Zhang, Wei Yu, Chunlong Xu, Yingsi Zhou, Yanfei Li, Minqing Cai, Qifang Wang, Mingxing Xue, Guoling Li, Kailun Fang, Hainan Zhang, Hui Yang · 发表于：Nature Biotechnology · 年份：2022 · DOI：10.1038/s41587-022-01419-7 · 被引用次数：234 · 研究领域：CRISPR and Genetic Engineering、RNA Interference and Gene Delivery、RNA regulation and disease