Medication Adherence and Blood Pressure Control Among Hypertensive Outpatients Attending a Tertiary Cardiovascular Hospital in Tanzania: A Cross-Sectional Study

作者：Pédrö Pallangyo, Makrina Komba, Zabella Mkojera, Peter Kisenge, Smita Bhalia, Henry Mayala, Engerasiya Kifai, Mwinyipembe K Richard, Khuzeima Khanbhai, Salma Wibonela, Jalack Millinga, Robert Yeyeye, Nelson F Njau, Thadei K Odemary, Mohamed Janabi · 发表于：Integrated Blood Pressure Control · 年份：2022 · DOI：10.2147/ibpc.s374674 · 被引用次数：15 · 研究领域：Medication Adherence and Compliance、Blood Pressure and Hypertension Studies、Pharmaceutical Practices and Patient Outcomes

Background: Notwithstanding the availability of effective treatments, asymptomatic nature and the interminable treatment length, adherence to medication remains a substantial challenge among patients with hypertension. Suboptimal adherence to BP-lowering agents is a growing global concern that is associated with the substantial worsening of disease, increased service utilization and health-care cost escalation. This study aimed to explore medication adherence and its associated factors among hypertension outpatients attending a tertiary-level cardiovascular hospital in Tanzania. Methods: The pill count adherence ratio (PCAR) was used to compute adherence rate. In descriptive analyses, adherence was dichotomized and consumption of less than 80% of the prescribed medications was used to denote poor adherence. Logistic regression analyses was used to determine factors associated with adherence. Results: A total of 849 outpatients taking antihypertensive drugs for ≥1 month prior to recruitment were randomly enrolled in this study. The mean age was 59.9 years and about two-thirds were females. Overall, a total of 653 (76.9%) participants had good adherence and 367 (43.2%) had their blood pressure controlled. Multivariate logistic regression analysis showed; lack of a health insurance (OR 0.5, 95% CI 0.3-0.7, p<0.01), last BP measurement >1 week (OR 0.6, 95% CI 0.4-0.8, p<0.01), last clinic attendance >1 month (OR 0.4, 95% CI 0.3-0.6, p<0.001), frequent unavailability of drugs (OR ...