Palladium metallaphotoredox-catalyzed 3-acylation of indole derivatives

作者：Xinmou Wang, Mo Yu, Hongjian Song, Yuxiu Liu, Qingmin Wang · 发表于：Chemical Communications · 年份：2022 · DOI：10.1039/d2cc03658d · 被引用次数：9 · 研究领域：Catalytic C–H Functionalization Methods、Radical Photochemical Reactions、Oxidative Organic Chemistry Reactions

dehydrogenative cross-coupling (CDC) reactions is the most efficient pathway. Here, we report a method for synthesis of 3-acyl indoles from aldehydes by a combination of photocatalysis and palladium catalysis. This mild, robust method is compatible with a wide array of functional groups and has a broad substrate scope. Our findings may inspire the development of new CDC reactions.