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Elucidating Mechanisms of Tolerance to Salmonella Typhimurium across Long-Term Infections Using the Collaborative Cross

作者:Kristin Scoggin, Jyotsana Gupta, Rachel Lynch, Aravindh Nagarajan, Manuchehr Aminian, Amy Peterson, L. Garry Adams, Michael Kirby, David W. Threadgill, Helene Andrews‐Polymenis · 发表于:mBio · 年份:2022 · DOI:10.1128/mbio.01120-22 · 被引用次数:12 · 研究领域:Salmonella and Campylobacter epidemiology、Escherichia coli research studies、Burkholderia infections and melioidosis

To survive a bacterial infection, an infected host can display resistance or tolerance. Resistance is indicated by a decrease in pathogen load, while for tolerance a high pathogen load is accompanied by minimal disease.