Comparison of wavefront-optimized and corneal wavefront-guided transPRK for high-order aberrations (>0.35 μm) in myopia

作者：Ting Shao, Hua Li, Jiafan Zhang, Huifeng Wang, Sai Liu, Keli Long · 发表于：Journal of Cataract & Refractive Surgery · 年份：2022 · DOI：10.1097/j.jcrs.0000000000001012 · 被引用次数：9 · 研究领域：Corneal surgery and disorders、Ophthalmology and Visual Impairment Studies、Retinal and Macular Surgery

PURPOSE: To compare the clinical outcomes, mainly including contrast sensitivity and high-order aberrations (HOAs), between wavefront-optimized (WFO) and corneal wavefront-guided (CWFG) transepithelial photorefractive keratectomy (transPRK) for preoperative HOAs >0.35 μm. SETTING: Qingdao Eye Hospital of Shandong First Medical University, Qingdao, Shandong, China. DESIGN: Prospective randomized controlled study. METHODS: 71 patients with preoperative total ocular and corneal aberrations >0.35 μm who underwent transPRK for the treatment of myopia and myopic astigmatism were randomly divided into the aberration optimization mode group (WFO group; 36 eyes) and the corneal wavefront-guided mode group (CWFG group; 35 eyes). Preoperative and postoperative visual outcome, refraction, contrast sensitivity, and HOAs were compared. RESULTS: 71 patients (71 eyes) who underwent transPRK were selected. The CWFG group had significantly lower total HOAs and coma values in the corneal aberration compared with the WFO group at 3 ( P = .009; P < .001) and 6 months postoperatively ( P = .006; P < .001). In addition, the CWFG group had significantly lower total HOAs and coma values in the whole-eye aberration compared with the WFO group at 3 ( P = .044; P = .004) and 6 months postoperatively ( P = .026; P = .001). The CWFG group had significantly better improvement in contrast sensitivity than the WFO group at spatial frequencies of 3 cycles per degree (cpd), 6 cpd, 12 cpd, and 18 cpd ( P = .005...