P1707: FACTORS ASSOCIATED WITH A LYMPHOMA DIAGNOSIS PRIOR TO BIOPSY

作者：A. Ejaz, C. Harris, Bing Tseu, Amy A. Kirkwood, S. Bhuva, Nia Taylor, C. A. Johnson, L. M. H. Wing, Graham P. Collins · 发表于：HemaSphere · 年份：2022 · DOI：10.1097/01.hs9.0000849684.28169.6d · 研究领域：Radiomics and Machine Learning in Medical Imaging

Background: Lymphoma is usually diagnosed on biopsy, but clues to a possible diagnosis may be found earlier in the diagnostic pathway when patients undergo CT imaging. Often CT scans are reported as showing likely lymphoma, leading to specialty referral before tissue diagnosis. A proportion of these patients have alternative diagnoses on biopsy, with a subsequent delay in referral to the most appropriate specialty. In the UK NHS Delivering Cancer Waiting Times: Good Practice Guide (2014), a top priority from patients for improving their experience was to be told they did not have cancer as soon as possible and, where they did have cancer, for a treatment plan to be made early. With the pressure of cancer waiting times and 2-week wait targets, any factors which can aid in earlier and more appropriate referral for patients will be valuable for health service providers and patients. Aims: Our aim was to identify factors that may predict a lymphoma diagnosis at the time of CT, prior to diagnostic biopsy. Our long-term goal is to create a diagnostic model which can be used to identify patients who are more likely to have lymphoma and who should be referred early to the appropriate team, leading to a more streamlined diagnostic pathway and improved patient experience. Methods: Between 1st July 2019-30th June 2021, 441 consecutive patients were identified who had undergone a CT scan reported as showing ‘likely lymphoma’. Patients were excluded if they were <18 years old or had a his...