Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

作者：Julia A. Belk, Winnie Yao, Nghi Ly, Katherine A. Freitas, Yanting Chen, Quanming Shi, Alfredo M. Valencia, Eric Shifrut, Nupura Kale, Kathryn E. Yost, Connor V. Duffy, Bence Dániel, Madeline A. Hwee, Zhuang Miao, Alan Ashworth, Crystal L. Mackall, Alexander Marson, Julia Carnevale, Santosha A. Vardhana, Ansuman T. Satpathy · 发表于：Cancer Cell · 年份：2022 · DOI：10.1016/j.ccell.2022.06.001 · 被引用次数：365 · 研究领域：CAR-T cell therapy research、Immune Cell Function and Interaction、T-cell and B-cell Immunology