Fast four‐dimensional cone‐beam computed tomography reconstruction using deformable convolutional networks

作者：Zhuoran Jiang, Yushi Chang, Zeyu Zhang, F Yin, Lei Ren · 发表于：Medical Physics · 年份：2022 · DOI：10.1002/mp.15806 · 被引用次数：14 · 研究领域：Advanced Radiotherapy Techniques、Medical Imaging Techniques and Applications、Advanced Neural Network Applications

BACKGROUND: Although four-dimensional cone-beam computed tomography (4D-CBCT) is valuable to provide onboard image guidance for radiotherapy of moving targets, it requires a long acquisition time to achieve sufficient image quality for target localization. To improve the utility, it is highly desirable to reduce the 4D-CBCT scanning time while maintaining high-quality images. Current motion-compensated methods are limited by slow speed and compensation errors due to the severe intraphase undersampling. PURPOSE: In this work, we aim to propose an alternative feature-compensated method to realize the fast 4D-CBCT with high-quality images. METHODS: We proposed a feature-compensated deformable convolutional network (FeaCo-DCN) to perform interphase compensation in the latent feature space, which has not been explored by previous studies. In FeaCo-DCN, encoding networks extract features from each phase, and then, features of other phases are deformed to those of the target phase via deformable convolutional networks. Finally, a decoding network combines and decodes features from all phases to yield high-quality images of the target phase. The proposed FeaCo-DCN was evaluated using lung cancer patient data. RESULTS: (1) FeaCo-DCN generated high-quality images with accurate and clear structures for a fast 4D-CBCT scan; (2) 4D-CBCT images reconstructed by FeaCo-DCN achieved 3D tumor localization accuracy within 2.5 mm; (3) image reconstruction is nearly real time; and (4) FeaCo-DCN a...