GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors

作者：Sijie Huang, Peiyu Xu, Dandan Shen, Ícaro A. Simon, Chunyou Mao, Yangxia Tan, Huibing Zhang, Kasper Harpsøe, Huadong Li, Yumu Zhang, Yumu Zhang, Xuekui Yu, Xuekui Yu, Yan Zhang, Yan Zhang, Yan Zhang, David E. Gloriam, H. Eric Xu · 发表于：Molecular Cell · 年份：2022 · DOI：10.1016/j.molcel.2022.05.031 · 被引用次数：154 · 研究领域：Receptor Mechanisms and Signaling、Protein Kinase Regulation and GTPase Signaling、Monoclonal and Polyclonal Antibodies Research