Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect

作者：Jia Liu, Mingcheng Sun, Yong Xia, Xiaopei Cui, Jingjing Jiang · 发表于：Food & Function · 年份：2022 · DOI：10.1039/d2fo00570k · 被引用次数：21 · 研究领域：Renal Diseases and Glomerulopathies、Chronic Kidney Disease and Diabetes

Phloretin has a protective effect on diabetic nephropathy. This beneficial effect possibly involves a non-hypoglycemic mechanism that preserves nephrin and podocin levels, thereby protecting podocytes and GFB from diabetic injury.