A Machine Learning-Based System for Real-Time Polyp Detection (DeFrame): A Retrospective Study

作者：Shuijiao Chen, Shuang Lu, Yingxin Tang, Dechun Wang, Xinzi Sun, Jun Yi, Benyuan Liu, Yu Cao, Yongheng Chen, Xiaowei Liu · 发表于：Frontiers in Medicine · 年份：2022 · DOI：10.3389/fmed.2022.852553 · 被引用次数：10 · 研究领域：Colorectal Cancer Screening and Detection、AI in cancer detection、COVID-19 diagnosis using AI

Background and Aims: Recent studies have shown that artificial intelligence-based computer-aided detection systems possess great potential in reducing the heterogeneous performance of doctors during endoscopy. However, most existing studies are based on high-quality static images available in open-source databases with relatively small data volumes, and, hence, are not applicable for routine clinical practice. This research aims to integrate multiple deep learning algorithms and develop a system (DeFrame) that can be used to accurately detect intestinal polyps in real time during clinical endoscopy. Methods: A total of 681 colonoscopy videos were collected for retrospective analysis at Xiangya Hospital of Central South University from June 2019 to June 2020. To train the machine learning (ML)-based system, 6,833 images were extracted from 48 collected videos, and 1,544 images were collected from public datasets. The DeFrame system was further validated with two datasets, consisting of 24,486 images extracted from 176 collected videos and 12,283 images extracted from 259 collected videos. The remaining 198 collected full-length videos were used for the final test of the system. The measurement metrics were sensitivity and specificity in validation dataset 1, precision, recall and F1 score in validation dataset 2, and the overall performance when tested in the complete video perspective. Results: A sensitivity and specificity of 79.54 and 95.83%, respectively, was obtained for ...