Lower Mediastinal Lymph Node Involvement Base on Eesophageal Invasion Length in Carcinoma of Esophagogastric Junction: A Systemic Review and Meta-Analysis

作者：Tasiken Baheti, Hainaer Yiaxiufu, Mingmin Zhang, Wei Huang · 年份：2022 · DOI：10.37766/inplasy2022.5.0147 · 研究领域：Esophageal Cancer Research and Treatment、Gastric Cancer Management and Outcomes、Lung Cancer Treatments and Mutations

Review question / Objective: Esophageal invasion is a significant predictor for lower mediastinal lymph node (LMLN) metastasis in carcinoma of esophagogastric junction(EGJ).The role between esophageal invasion length(EIL) and LMLN involvement still is a debate in EGJ carcinoma.This systemic review aim to review and summarize the incidence of LMLN metastasis or recurrence base on different EIL in EGJ carcinoma.Eligibility criteria: Studies were included base on the following criteria:histologically confirmed EGJ carcinoma, underwent LMLN dissection and report the involement rate of LMLN, report the EIL in centimeters and LMLN involvement rate in different EIL and case numbers in each EIL group.Analysis base on other studies, not English articles, reviews, case reports, data inconsistent, EIL wasn't subgrouped in centimeters and midiastinal lymph node was's subgrouped are exclusion criteria.INPLASY registration number: This protocol was registered with the International Platform of Registered Systematic Review and Meta-Analysis Protocols (INPLASY) on 26 May 2022 and was last u p d a t e d o n 2 6 M a y 2 0 2 2 ( r e g i s t r a t i o n n u m b e r INPLASY202250147).