The COMBAT project: controlling and progressively minimizing the burden of vector-borne animal trypanosomosis in Africa

作者：Alain Boulangé, Veerle Lejon, David Berthier, Sophie Thévenon, Geoffrey Gimonneau, Marc Desquesnes, Samuel Eneọjọ Abah, Prudenciène Agboho, Kalinga Chilongo, Tsegaye Gebre, Assane Guèye Fall, Dramane Kaba, Stefan Magez, Daniel Masiga, Enock Matovu, Aldjibert Moukhtar, Luís Neves, Pamela A. Olet, Soumaïla Pagabeleguem, William Shereni, Brice Sorli, Moeti O. Taioe, María Teresa Tejedor‐Junco, Rehab Yagi, Philippe Solano, Giuliano Cecchi · 发表于：Open Research Europe · 年份：2022 · DOI：10.12688/openreseurope.14759.1 · 被引用次数：14 · 研究领域：Trypanosoma species research and implications、Vector-Borne Animal Diseases、Viral Infections and Vectors

Vector-borne diseases affecting livestock have serious impacts in Africa. Trypanosomosis is caused by parasites transmitted by tsetse flies and other blood-sucking Diptera . The animal form of the disease is a scourge for African livestock keepers, is already present in Latin America and Asia, and has the potential to spread further. A human form of the disease also exists, known as human African trypanosomosis or sleeping sickness. Controlling and progressively minimizing the burden of animal trypanosomosis (COMBAT) is a four-year research and innovation project funded by the European Commission, whose ultimate goal is to reduce the burden of animal trypanosomosis (AT) in Africa. The project builds on the progressive control pathway (PCP), a risk-based, step-wise approach to disease reduction or elimination. COMBAT will strengthen AT control and prevention by improving basic knowledge of AT, developing innovative control tools, reinforcing surveillance, rationalizing control strategies, building capacity, and raising awareness. Knowledge gaps on disease epidemiology, vector ecology and competence, and biological aspects of trypanotolerant livestock will be addressed. Environmentally friendly vector control technologies and more effective and adapted diagnostic tools will be developed. Surveillance will be enhanced by developing information systems, strengthening reporting, and mapping and modelling disease risk in Africa and beyond. The socio-economic burden of AT will be ...