Detection of SARS-CoV-2 contamination in the operating room and birthing room setting: a cross-sectional study

作者：Patricia E. Lee, Robert Kozak, Nasrin Alavi, Hamza Mbareche, Rose Kung, Kellie E. Murphy, Darian Perruzza, Stephanie Jarvi, Elsa Salvant, Noor Niyar N. Ladhani, Albert Yee, Louise-Helene Gagnon, Richard Jenkinson, Grace Y. Liu · 发表于：CMAJ Open · 年份：2022 · DOI：10.9778/cmajo.20210321 · 被引用次数：7 · 研究领域：Infection Control and Ventilation、COVID-19 Impact on Reproduction、COVID-19 and healthcare impacts

BACKGROUND: The exposure risks to front-line health care workers caring for patients with SARS-CoV-2 infection undergoing surgery or obstetric delivery are unclear, and an understanding of sample types that may harbour virus is important for evaluating risk. We sought to determine whether SARS-CoV-2 viral RNA from patients with SARS-CoV-2 infection undergoing surgery or obstetric delivery was present in the peritoneal cavity of male and female patients, in the female reproductive tract, in the environment of the surgery or delivery suite (surgical instruments or equipment used, air or floors), and inside the masks of the attending health care workers. METHODS: We conducted a cross-sectional study from November 2020 to May 2021 at 2 tertiary academic Toronto hospitals, during urgent surgeries or obstetric deliveries for patients with SARS-CoV-2 infection. The presence of SARS-CoV-2 viral RNA in patient, environmental and air samples was identified by real-time reverse transcription polymerase chain reaction (RT-PCR). Air samples were collected using both active and passive sampling techniques. The primary outcome was the proportion of health care workers' masks positive for SARS-CoV-2 RNA. We included adult patients with positive RT-PCR nasal swab undergoing obstetric delivery or urgent surgery (from across all surgical specialties). RESULTS: A total of 32 patients (age 20-88 yr) were included. Nine patients had obstetric deliveries (6 cesarean deliveries), and 23 patients (14...