Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial

作者：Cameron R. Wolfe, Kay M Tomashek, Thomas F. Patterson, Carlos A. Gómez, Vincent C. Marconi, Mamta K. Jain, Otto O. Yang, Catharine I. Paules, Guillermo M. Ruiz Palacios, Robert Grossberg, Michelle Harkins, Richard A. Mularski, Nathaniel Erdmann, Uriel Sandkovsky, Eyad Almasri, Justino Regalado Pineda, Alexandra W. Dretler, Diego López de Castilla, Angela R Branche, Pauline K. Park, Aneesh K. Mehta, William R. Short, Susan McLellan, Susan Kline, Nicole M. Iovine, Hana M. El Sahly, Sarah B. Doernberg, Myoung‐don Oh, Nikhil Huprikar, Elizabeth Hohmann, Colleen F. Kelley, Mark Holodniy, Eu Suk Kim, Daniel A. Sweeney, Robert W. Finberg, Kevin A. Grimes, Ryan C. Maves, Emily R. Ko, John J. Engemann, Barbara S. Taylor, Philip O. Ponce, LuAnn Larson, Dante P. Melendez, Allan Seibert, Nadine Rouphael, Joslyn K. Strebe, Jesse L. Clark, Kathleen G. Julian, Alfredo Ponce‐de‐León, Anabela Cardoso, Stephanie de Bono, Robert L. Atmar, Anuradha Ganesan, Jennifer L Ferreira, Michelle Green, Mat Makowski, Tyler Bonnett, Tatiana Beresnev, Varduhi Ghazaryan, Walla Dempsey, Seema Nayak, Lori E. Dodd, John H. Beigel, André C. Kalil, Lana Wahid, Emmanuel B. Walter, Akhila G. Belur, Grace R. Dreyer, Jan E. Patterson, Jason E. Bowling, Danielle O. Dixon, Angela Hewlett, Robert Odrobina, Jakrapun Pupaibool, Satish Mocherla, Suzana Lazarte, Meilani Cayabyab, Rezhan H. Hussein, Reshma Golamari, Kaleigh L. Krill, Sandra Rajme‐López, Paul Riska, Barry S. Zingman, Grégory Mertz, Néstor Sosa, Paul Goepfert, Mezgebe Berhe, Emma Dishner, Mohamed Fayed, Kinsley Hubel, José Arturo Martínez-Orozco, Nora Bautista Felix, Sammy T. Elmor, Amer Ryan Bechnak, Youssef Saklawi, Jason W. Van Winkle, Diego F. Zea, Maryrose Laguio‐Vila, Edward E. Walsh, Ann R. Falsey, Karen Carvajal, Robert C. Hyzy, Sinan Hanna, Norman Olbrich, Jessica Traenkner, Colleen S. Kraft, Pablo Tebas, Jillian Baron, Corri B. Levine, Joy Nock, Joanne Billings, Hyun Kim, Marie‐Carmelle Elie, Jennifer A. Whitaker, Anne F. Luetkemeyer, Jay Dwyer, Emma Bainbridge, Pyoeng Gyun Choe, Chang Kyung Kang, Nikolaus Jilg, Valeria D Cantos, Divya Bhamidipati, Srinivasa Nithin Gopalsamy, Aarthi Chary, Jongtak Jung, Kyoung‐Ho Song, Hong Bin Kim, Constance A. Benson, Kimberly McConnell, Jennifer Wang, Mireya Wessolossky, Katherine K. Perez, Taryn A Eubank, Catherine M Berjohn, Gregory Utz, Patrick Jackson, Taison D. Bell, Heather M. Haughey, Abeer Moanna, Sushma K. Cribbs, Telisha Harrison, Christopher Colombo, Christina Schofield, Rhonda E Colombo, Victor F. Tapson, Jonathan Grein, Fayyaz S. Sutterwala, Dilek İnce, Patricia Winokur, Monica Fung, Hannah Jang, David Wyles, Maria G. Frank, Ellen Sarcone, Henry Neumann, Anand Viswanathan, Sarah Hochman, Mark J. Mulligan, Benjamin Eckhardt, Ellie Carmody, Neera Ahuja, Kari C. Nadeau, Dávid Švec, Jeffrey Macaraeg, Lee Morrow, Dave Quimby, Mary Bessesen, Lindsay B. Nicholson, Jill Adams, Princy Kumar, Allison Lambert, Henry Arguinchona, Radica Z. Alicic, Sho Saito, Norio Ohmagari, Ayako Mikami, David Chien Lye, Tau Hong Lee, Po Ying Chia, Lanny Hsieh, Alpesh Amin, Miki Watanabe, Keith Candiotti, José G. Castro, Maria A. Antor, Tida Lee, Tahaniyat Lalani, Richard Novák, Andrea Wendrow, Scott Borgetti, Sarah L. George, Daniel F. Hoft, James D. Brien, Stuart H. Cohen, George R. Thompson, Melony Chakrabarty, Faheem W. Guirgis, Richard T. Davey, Jocelyn Voell, Jeffrey R. Strich, David A Lindholm, Katrin Mende, Trevor R. Wellington, Rekha R. Rapaka, Jennifer Husson, Andrea R. Levine, Seow Yen Tan, Humaira Shafi, Jaime Chien, David C. Hostler, Jordanna Hostler, Brian T. Shahan, David H. Adams, Anu Osinusi, Huyen Cao, Timothy Burgess, Julia S Rozman, Kevin K. Chung, Christina Nieuwoudt, Jill A. El-Khorazaty, Heather C. Hill, Stephanie Pettibone, Nikki Gettinger, Theresa Engel, Teri Lewis, Jing Wang, Gregory A. Deye, Effie Nomicos, Rhonda Pikaart-Tautges, Mohammed Elsafy, Robert Jurao, Hyung Il Koo, Michael A. Proschan, Tammy Yokum, Janice Arega, Ruth H. Florese · 发表于：The Lancet Respiratory Medicine · 年份：2022 · DOI：10.1016/s2213-2600(22)00088-1 · 被引用次数：128 · 研究领域：COVID-19 Clinical Research Studies、Respiratory Support and Mechanisms、Long-Term Effects of COVID-19