Biological Functions and Applications of Antimicrobial Peptides

作者：Libo Jin, Hao Dong, Da Sun, Lei Wang, Linkai Qu, Sue Lin, Qinsi Yang, Xingxing Zhang · 发表于：Current Protein and Peptide Science · 年份：2022 · DOI：10.2174/1389203723666220519155942 · 被引用次数：22 · 研究领域：Antimicrobial Peptides and Activities、Protein Hydrolysis and Bioactive Peptides、Insect Utilization and Effects

Despite antimicrobial resistance, which is attributed to the misuse of broad-spectrum antibiotics, antibiotics can indiscriminately kill pathogenic and beneficial microorganisms. These events disrupt the delicate microbial balance in both humans and animals, leading to secondary infections and other negative effects. Antimicrobial peptides (AMPs) are functional natural biopolymers in plants and animals. Due to their excellent antimicrobial activities and absence of microbial resistance, AMPs have attracted enormous research attention. We reviewed the antibacterial, antifungal, antiviral, antiparasitic, as well as antitumor properties of AMPs and research progress on AMPs. In addition, we highlighted various recommendations and potential research areas for their progress and challenges in practical applications.