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Diversity and Long-Term Dynamics of Human Blood Anelloviruses

作者:Joanna Kaczorowska, Martin Deijs, Michelle Klein, Margreet Bakker, Maarten F. Jebbink, Mila Sparreboom, Cormac M. Kinsella, Anne L. Timmerman, Lia van der Hoek · 发表于:Journal of Virology · 年份:2022 · DOI:10.1128/jvi.00109-22 · 被引用次数:45 · 研究领域:Animal Virus Infections Studies、Virus-based gene therapy research、Plant Virus Research Studies

Knowledge of the persistence of AVs in humans is crucial to our understanding of the nature of AV infection (chronic or acute) and the role of AV in the host. We therefore investigated the dynamics of anellovirus infection in two healthy people followed up for 30 years. Our findings suggest that the human blood anellovirus virome (anellome) remains stable and personal for decades.