A guide to the organ-on-a-chip

作者：Chak Ming Leung, Pim de Haan, Kacey Ronaldson-Bouchard, Ge-Ah Kim, Jihoon Ko, Hoon Suk Rho, Zhu Chen, Pamela Habibović, Noo Li Jeon, Shuichi Takayama, Michael Louis Shuler, Gordana Vunjak‐Novakovic, Olivier Frey, Elisabeth M. J. Verpoorte, Yi‐Chin Toh · 发表于：Nature Reviews Methods Primers · 年份：2022 · DOI：10.1038/s43586-022-00118-6 · 被引用次数：1093 · 研究领域：3D Printing in Biomedical Research、Innovative Microfluidic and Catalytic Techniques Innovation、Neuroscience and Neural Engineering

Organs-on-chips are microfluidic systems containing miniature tissues with the aim of mimicking human physiology for a range of biomedical and therapeutic applications. Leung, de Haan et al. report practical tips to inform design and operational decisions during the implementation of organ-on-a-chip systems.