Refractory Mycoplasma pneumoniae Pneumonia in Children: Early Recognition and Management

作者：Lin Tong, Shumin Huang, Chen Zheng, Yuanyuan Zhang, Zhimin Chen · 发表于：Journal of Clinical Medicine · 年份：2022 · DOI：10.3390/jcm11102824 · 被引用次数：147 · 研究领域：Pneumonia and Respiratory Infections、Respiratory viral infections research、Bacterial Infections and Vaccines

infection that has attracted increasing universal attention in recent years. The pathogenesis of RMPP remains unknown, but the excessive host immune responses as well as macrolide resistance of M. pneumoniae might play important roles in the development of RMPP. To improve the prognosis of RMPP, it is mandatory to recognize RMPP in the early stages, and the detection of macrolide-resistant MP, clinical unresponsiveness to macrolides and elevated proinflammatory cytokines might be clues. Timely and effective anti-mycoplasmal therapy and immunomodulating therapy are the main strategies for RMPP.