Face Mask Use and Control of Respiratory Virus Transmission in Households

作者：Chandini Raina MacIntyre, Simon Cauchemez, Dominic Edmund Dwyer, Holly Seale, Pamela Cheung, Gary J. Browne, Michael Fasher, James Wood, Zhanhai Gao, Robert Booy, Neil M. Ferguson · 发表于：Emerging infectious diseases · 年份：2009 · DOI：10.3201/eid1502.081166 · 被引用次数：336 · 研究领域：Infection Control and Ventilation、COVID-19 epidemiological studies、Viral Infections and Outbreaks Research

Many countries are stockpiling face masks for use as a nonpharmaceutical intervention to control virus transmission during an infl uenza pandemic.We conducted a prospective cluster-randomized trial comparing surgical masks, non-fi ttested P2 masks, and no masks in prevention of infl uenzalike illness (ILI) in households.Mask use adherence was self-reported.During the 2006 and 2007 winter seasons, 286 exposed adults from 143 households who had been exposed to a child with clinical respiratory illness were recruited.We found that adherence to mask use signifi cantly reduced the risk for ILI-associated infection, but <50% of participants wore masks most of the time.We concluded that household use of face masks is associated with low adherence and is ineffective for controlling seasonal respiratory disease.However, during a severe pandemic when use of face masks might be greater, pandemic transmission in households could be reduced. H ighly pathogenic avian infl uenza virus A (H5N1) con-tinues to spread globally, posing a serious human pandemic threat.In the event of an infl uenza pandemic or other emerging respiratory disease such as severe acute respira- Face Mask Use and Control of Respiratory Virus Transmission in Households