Acupuncture with Rehabilitation in the Treatment of Ischemic Stroke Recovery: A Randomized Controlled Trial

作者：Lixia Li, Weifeng Zhu, Guohua Lin, Chuyun Chen, Donghui Tang, Shiyu Lin, Xiaorong Weng, Liqin Xie, Lihong LU, Weilin Li · 发表于：Research Square (Research Square) · 年份：2019 · DOI：10.21203/rs.2.177/v3 · 研究领域：Acupuncture Treatment Research Studies、Botulinum Toxin and Related Neurological Disorders、Healthcare and Venom Research

Background: Acupuncture is a well known treatment for ischemic stroke recovery, but evidence of its effectiveness remains limited.Methods: Rehabilitation training was provided to a control group.In Arm 1 and Arm 2, acupoint schemes were determined by a consensus of acupuncture experts and previous clinical research.Arm 1 was based on an acupoint summary of ancient literature, and Arm 2 was based on the summary of effective acupuncture points from modern RCT literature.Acupuncture was given on the acupoint.After acupuncture, the needles were left in for 30 minutes, and checked every 10 minutes.The three groups received treatment once a day, 5 times a week, for 2 weeks.The primary outcome was the National Institute of Health stroke scale (NIHSS), and the secondary outcomes were the Barthel index (BI) and the modi ed Ashworth scale (MAS).Outcomes were observed in patients both before and after treatment.Results: A total of 497 patients with ischemic stroke were randomized into either Arm 1 (159 cases), Arm 2 (173 cases) or a control group (165 cases).After 2 weeks of treatment, the NIHSS scores for Arm 1 were lower than those of the control group (P=0.017); the BI scores were higher in Arm 2 than they were in the control group (P=0.020).Additionally, there was no signi cant difference between Arm 1 and the control group for either the BI scores or the modi ed Ashworth scale scores (P>0.05).Conclusion:The clinical e cacy of Arm 1 and Arm 2 (acupuncture groups) was superior to tha...