Acoustic Microfluidics

作者：Peiran Zhang, Hunter Bachman, Adem Özçelik, Tony Jun Huang · 发表于：Annual Review of Analytical Chemistry · 年份：2020 · DOI：10.1146/annurev-anchem-090919-102205 · 被引用次数：317 · 研究领域：Microfluidic and Bio-sensing Technologies、Microfluidic and Capillary Electrophoresis Applications、Nanopore and Nanochannel Transport Studies

Acoustic microfluidic devices are powerful tools that use sound waves to manipulate micro- or nanoscale objects or fluids in analytical chemistry and biomedicine. Their simple device designs, biocompatible and contactless operation, and label-free nature are all characteristics that make acoustic microfluidic devices ideal platforms for fundamental research, diagnostics, and therapeutics. Herein, we summarize the physical principles underlying acoustic microfluidics and review their applications, with particular emphasis on the manipulation of macromolecules, cells, particles, model organisms, and fluidic flows. We also present future goals of this technology in analytical chemistry and biomedical research, as well as challenges and opportunities.