Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance

作者：National Diabetes Data Group · 发表于：Diabetes · 年份：1979 · DOI：10.2337/diab.28.12.1039 · 被引用次数：4954 · 研究领域：Diabetes and associated disorders、Diet, Metabolism, and Disease、Metabolism, Diabetes, and Cancer

A classification of diabetes and other categories of glucose intolerance, based on contemporary knowledge of this heterogeneous syndrome, was developed by an international workgroup sponsored by the National Diabetes Data Group of the NIH. This classification, and revised criteria for the diagnosis of diabetes, were reviewed by the professional members of the American Diabetes Association, and similar versions were circulated by the British Diabetic Association, the Australian Diabetes Society, and the European Association for the Study of Diabetes. The ADA has endorsed the proposals of the international workgroup, and the Expert Committee on Diabetes of the World Health Organization has accepted its substantive recommendations. It is proposed that this classification be used as a uniform framework in which to conduct clinical and epidemiologie research so that more meaningful and comparative data will be obtained on the scope and impact of the various forms of diabetes and other classes of glucose intolerance. Medical treatment of diabetes is not considered in this paper, and the classification is not an attempt to define guidelines for therapy of patients. The salient changes proposed in the classification are that 1. The insulin-dependent, ketosis-prone type of diabetes, which is associated with increased or decreased frequency of certain histocompatibility antigens (HLA) on chromosome 6 and with islet cell antibodies, be considered a distinct subclass of diabetes [insulin...