Highly Stereoselective Synthesis of 1,3‐Dienes through an Aryl to Vinyl 1,4‐Palladium Migration/Heck Sequence

作者：Tianjiao Hu, Mengyao Li, Qian Zhao, Chen‐Guo Feng, Guo‐Qiang Lin · 发表于：Angewandte Chemie · 年份：2018 · DOI：10.1002/ange.201801963 · 被引用次数：28 · 研究领域：Catalytic C–H Functionalization Methods、Catalytic Cross-Coupling Reactions、Catalytic Alkyne Reactions

Abstract An efficient aryl to vinyl 1,4‐palladium migration/Heck sequence was developed for the stereoselective synthesis of 1,3‐dienes. High stereoselectivity was observed not only for 1,3‐dienes bearing two similar aryl groups at terminal positions, but also for those with configurations shown to be unfavorable with previous methods.