Fat Transport in Lipoproteins — An Integrated Approach to Mechanisms and Disorders

作者：Donald S. Fredrickson, Robert I. Levy, Robert S. Lees · 发表于：New England Journal of Medicine · 年份：1967 · DOI：10.1056/nejm196701192760305 · 被引用次数：534 · 研究领域：Cancer, Lipids, and Metabolism、Diabetes, Cardiovascular Risks, and Lipoproteins、Lipid metabolism and disorders

HyperlipoproteinemiaDefinitionsUp to this point we have concentrated on laying the support for 2 generalizations. The first is that, with the exception of free fatty acid concentrations, which have no lipoprotein equivalents, all abnormalities in plasma lipid concentrations or dyslipidemia can be translated into dyslipoproteinemia. The second is that the shift of emphasis to lipoproteins offers distinct advantages in the recognition and management of such disorders. We have already discussed the relatively few cases in which hypolipoproteinemia is a clinical problem, and the remainder of the review will be devoted to hyperlipoproteinemia.Hyperlipoproteinemia (hyperlipidemia) falls into 2 . . .