Increased Pharyngeal Bacterial Colonization During Viral Illness

作者：Carlos H. Ramirez-Ronda · 发表于：Archives of Internal Medicine · 年份：1981 · DOI：10.1001/archinte.1981.00340130043013 · 被引用次数：47 · 研究领域：Respiratory viral infections research、Otolaryngology and Infectious Diseases、Pneumonia and Respiratory Infections

• The oropharyngeal colonization byStaphylococcus aureusand Gram-negative bacilli (GNB) and its duration were studied in 89 house staff officers, with biweekly quantitative cultures for 11 months. Eighty-two episodes of upper respiratory tract infection were documented during the study period. The oropharyngeal colonization during illness-free periods ranged from 12% to 18% for GNB and from 5% to 14% forS aureus. During an episode of upper respiratory tract infection, the oropharyngeal colonization of GNB increased to 60%;S aureuscolonization increased to 43%. The colonization with both GNB andS aureuswas transient and lasted for approximately two weeks. The increased colonization byS aureusand GNB during a viral respiratory tract infection may be a factor contributing to the increased risk of pneumonia in patients with this condition. (Arch Intern Med1981;141:1599-1603)