Trans-abdominal ultrasound features of the newly named intraductal papillary neoplasm of the bile duct

作者：Xian-Shui Fu, Mengna He, Yan-Xiao Chang, Jing Zhang, Ke Lv, Huabin Zhang, Li Tan, Yuxin Jiang · 发表于：Translational Cancer Research · 年份：2017 · DOI：10.21037/tcr.2017.09.33 · 研究领域：Cholangiocarcinoma and Gallbladder Cancer Studies、Genetic and Kidney Cyst Diseases、Pediatric Hepatobiliary Diseases and Treatments

Background: Intraductal papillary neoplasm of the bile duct (IPMN-B) is a rare cystic neoplasm of the liver. This study retrospectively reviewed a relatively large sample of IPMN-B cases for diagnostic clinical or trans-abdominal ultrasound features.Methods: The medical records of 20 pathologically confirmed IPMN-B cases were reviewed. Serum concentrations of carbohydrate antigen 19-9 (CA19-9), carcinoembryonic antigen (CEA), and alpha-fetoprotein (AFP) were evaluated, and images of conventional trans-abdominal ultrasound. According to the relationship between the hepatic mass and the dilated bile duct, we classified cases as type I–IV: I, non-tumor; II, asymmetrical; III, symmetrical; and IV, aneurismal dilation. The clinical and trans-abdominal ultrasound characteristics of these types were compared.Results: The clinical features were non-specific; only malignant cases showed CA19-9 or CEA elevation. Three, 9, 3, and 5 cases were types I, II, III, and IV, respectively, and the diameters of the dilated common bile ducts were 2.27±1.08, 1.82±0.79, 0.57±0.15, and 0.68±0.08 cm. The dilations of the common bile duct of types I and II were significantly larger than that of III and IV. Pathologically, 15, 3, and 2 cases were adenocarcinoma, benign, and two border adenomas. The pathological distribution among the four types differed significantly for all of the benign cases and 50% of the border adenomas were type I or II; types III and IV more aggressively progressed to adenocarci...