Lactic Acidosis

作者：Jeffrey A. Kraut, Nicolaos E. Madias · 发表于：New England Journal of Medicine · 年份：2014 · DOI：10.1056/nejmra1309483 · 被引用次数：858 · 研究领域：Renal function and acid-base balance、Sepsis Diagnosis and Treatment、Hemodynamic Monitoring and Therapy

When lactic acidosis accompanies low-flow states or sepsis, mortality rates increase sharply. This review summarizes our current understanding of the pathophysiological aspects of lactic acidosis, as well as the approaches to its diagnosis and management.