Hepatocellular Carcinoma

作者：Augusto Villanueva · 发表于：New England Journal of Medicine · 年份：2019 · DOI：10.1056/nejmra1713263 · 被引用次数：4714 · 研究领域：Liver Disease Diagnosis and Treatment、Hepatocellular Carcinoma Treatment and Prognosis、Hepatitis B Virus Studies

Primary liver cancer is the fourth most common tumor worldwide. Hepatocellular carcinoma occurs mainly in the context of cirrhosis, hepatitis B or C virus infection, or nonalcoholic steatohepatitis. Underlying liver disease limits therapeutic efficacy.