Pneumococcal vaccine after 15 years of use. Another view

作者：David S. Fedson · 发表于：Archives of Internal Medicine · 年份：1994 · DOI：10.1001/archinte.154.22.2531 · 被引用次数：71 · 研究领域：Pneumonia and Respiratory Infections、Vaccine Coverage and Hesitancy、Immunodeficiency and Autoimmune Disorders

IN A recent Commentary, Hirschmann and Lipsky1reviewed pneumococcal vaccine after 15 years of use in the United States. Following their evaluation of prospective vaccine trials, retrospective studies, and projections of vaccine effectiveness, they stated that "no conclusive evidence has yet emerged that the pneumococcal vaccine is effective inanygroup in the United States." In their judgment, "the evidence justifies not vaccinating immunocompromised or elderly populations" with pneumococcal vaccine. While most observers would agree that the available evidence on the clinical effectiveness of pneumococcal vaccination is incomplete, the evidence has been the subject of ongoing critical review by several expert groups, including the Advisory Committee on Immunization Practices,2the American College of Physicians/ Infectious Diseases Society of America Task Force on Adult Immunization,3the National Advisory Committee on Immunization in Canada,4and a Technical Advisory Group to the World Health Organization Regional Office for Europe.5