Prevalence and risk of atrial fibrillation in China: A national cross-sectional epidemiological study

作者：Shaobo Shi, Yanhong Tang, Qingyan Zhao, Hong Yan, Bin Yu, Qiangsun Zheng, Yi‐Gang Li, Liangrong Zheng, Yiqiang Yuan, Jingquan Zhong, Jian Xu, Yanqing Wu, Jing Xu, Lin Chen, Shufeng Li, Jian Jiang, Jingfeng Wang, Jie Fan, Minglong Chen, Baopeng Tang, Wei Li, Qiang Wu, Bei Shi, Shenghua Zhou, Xingsheng Zhao, Yuehui Yin, Zheng Zhang, Guoqiang Zhong, Xuebin Han, Fan Liu, Ming Wu, Lianjun Gao, Bo Yang, He Huang, Congxin Huang · 发表于：The Lancet Regional Health - Western Pacific · 年份：2022 · DOI：10.1016/j.lanwpc.2022.100439 · 被引用次数：136 · 研究领域：Atrial Fibrillation Management and Outcomes、Cardiovascular Disease and Adiposity、Healthcare Systems and Public Health

Background Atrial fibrillation (AF) is the most common persistent cardiac arrhythmia. This study aimed to estimate its prevalence and explore associated factors in adults aged 18 years or older in China. Methods Study data were derived from a national sample from July 2020 to September 2021. Participants were recruited using a multistage stratified sampling method from twenty-two provinces, autonomous regions, and municipalities in China. AF was determined based on a history of diagnosed AF or electrocardiogram results. Findings A total of 114,039 respondents were included in the final analysis with a mean age of 55 years (standard deviation 17), 52·1% of whom were women. The crude prevalence of AF was 2·3% (95% confidence interval [CI] 1·7-2·8) and increased with age. The age-standardized AF prevalence was 1·6% (95% CI 1·6-1·7%) overall, and 1·7% (1·6-1·8%), 1·4% (1·3-1·5%), 1·6% (95% CI 1·5-1·7%), and 1·7% (1·6-1·9%) in men, women, urban areas, and rural areas, respectively. The prevalence was higher in the central regions (2·5%, 2·3-2·7%) than in the western regions (1·5%, 1·0-2·0%) and eastern regions (1·1%, 1·0-1·2%) in the overall population, either in the gender or residency subgroups. The associated factors for AF included age (per 10 years; odds ratio 1·41 [95% CI 1·38-1·46]; p < 0·001), men (1·34 [1·24-1·45]; p < 0·001), hypertension (1·22 [1·12-1·33]; p < 0·001), coronary heart disease (1·44 [1·28-1·62]; p < 0·001), chronic heart failure (3·70 [3·22-4·26]; p < 0·00...