Evaluating two respiratory correction methods for abdominal PET/MRI imaging

作者：Weiwei Ruan, Fang Liu, Xun Sun, Fan Hu, Tingfan Wu, Yongxue Zhang, Xiaoli Lan · 发表于：EJNMMI Physics · 年份：2022 · DOI：10.1186/s40658-022-00430-w · 被引用次数：5 · 研究领域：Medical Imaging Techniques and Applications、Radiomics and Machine Learning in Medical Imaging、Advanced Radiotherapy Techniques

Abstract Background To evaluate two respiratory correction methods for abdominal PET/MRI images and further to analyse the effects on standard uptake values (SUVs) of respiratory motion correction, 17 patients with 25 abdominal lesions on 18 F-FDG PET/CT were scanned with PET/MRI. PET images were reconstructed using end-expiratory respiratory gating and multi-bin respiratory gating. Meanwhile, full data and the first 3 min and 20 s of data acquired both without respiratory gating were reconstructed for evaluation. Five parameters, including the SUV max and SUV mean in the lesions, the SUV mean and standard deviation (SD) in the background, and the signal-to-noise ratio (SNR), were calculated and used for statistical comparisons. The differences in multi-bin respiratory gating and reconstruction of full data, relative to the reconstruction of the first 3 min and 20 s of data acquired, were calculated. Results Compared with PET/CT, the longer scanning time of abdominal PET/MRI makes respiratory motion correction necessary. The multi-bin respiratory gating correction could reduce the PET image blur and increase the SUV max (11.98%) and SUV mean (13.12%) of the lesions significantly ( p = 0.00), which was much more effective than end-expiratory respiratory gating for abdominal PET/MRI. The added value of SUV max caused by respiratory motion correction has no significant difference compared with that caused by count loss with the correction ( p = 0.39), which was rarely reported b...