Assessing Visceral Obesity and Abdominal Adipose Tissue Distribution in Healthy Populations Based on Computed Tomography: A Large Multicenter Cross-Sectional Study

作者：Ming Kong, Manman Xu, Ying Zhou, Nan Geng, Ning Lin, Wenyan Song, Shanshan Li, Yuetong Piao, Zuoqing Han, Rong Guo, Chao Yang, Nan Luo, Zhong Wang, Lei Ma, Quanxiao Xu, Lili Wang, Wanchun Qiu, Junfeng Li, Daimeng Shi, Eddie C. Cheung, Rongkuan Li, Yu Chen, Zhongping Duan · 发表于：Frontiers in Nutrition · 年份：2022 · DOI：10.3389/fnut.2022.871697 · 被引用次数：50 · 研究领域：Adipokines, Inflammation, and Metabolic Diseases、Diabetes, Cardiovascular Risks, and Lipoproteins、Cardiovascular Disease and Adiposity

Objective Abdominal adipose is closely related to many endocrine and metabolic diseases. The aim of this study was to analyze the distribution of abdominal adipose tissue in a healthy population in northern China determined by abdominal computed tomography (CT). Methods Data for this study were obtained from a multicenter, retrospective, cross-sectional study that collected abdominal CT scans of 1787 healthy individuals from 4 representative cities in northern China. Areas of visceral adipose tissue (VATA) and subcutaneous adipose tissue (SATA) were obtained by measuring CT images at the level of the 3rd lumbar vertebra. Visceral adipose tissue index (VATI) and subcutaneous adipose index (SATI) were obtained by normalizing the square of height to analyze the distribution of the above indexes and visceral obesity among different body mass index (BMI), gender and age. Results The mean age of this healthy population was 45.3 ± 15.2 years and the mean BMI was 23.5 ± 3.2 kg/m 2 , with 902 men and 885 women. Compared with women, men had a significantly higher median VATA (120.9 vs. 67.2 cm 2 ), VATI (39.1 vs. 25.6 cm 2 /m 2 ) and a significantly higher percentage of visceral adiposity (VATA ≥ 100 cm 2 ) (60.8 vs. 30.4%), while women had significantly higher SATA (116.9 vs. 146.7 cm 2 ) and SATI (38.8 vs. 55.8 cm 2 /m 2 ) than men. Whether men or women, VATI was positively correlated with age. Interestingly, SATI was weakly positively correlated with age in women, while SATI was wea...